A message from my son…

…Barry, who  has a xolo named Finn.  Finn had a dark patch of skin on his belly and by his hind legs.

“YOU REALLY NEED to add this to your site mom! This stuff saved us!”

Finn had the ‘black skin disease’, and we were at the end of our wits, we tried everything (diet, applications, home remedies – and it only got worse). He was scratching himself to bits. You really need to recommend this to your xolo people! It should go on the health page i think.
(The term ‘black skin disease’ , as used in this message, was not arrived at as a result of a veterinarian’s examination.  It was found on an internet blog. This cream
would probably be helpful with many different skin issues.)

Xolo Info. – Taping puppies ears.

The Xolo ear usually needs temporary support to grow erect as the puppy grows.  Many different parts of the puppy’s body are competing for the available nutrients and calcium that make the ears stand erect.  When the adult teeth come in and have formed, then there is more available calcium for the ears and they generally are erect by 6 months of age, if not before.  We usually begin taping the ears at 3 weeks of age, very early, so that the pups learn to tolerate the slight discomfort involved.  Here we have photos of 4 week old puppies that have their ears taped and another photo showing how they look when the tape is removed after two days.

A bit about grooming your Xoloitzcuintle.

Shampoo for Xolos with normal skin.

Into an empty gallon jug put:

1 bottle Ivory liquid or Planet liquid. (25 oz. bottle)

2 oz. glycerin……2 oz. white vinegar…….& fill jug to 2/3 full with water.

If shampoo is for coated dogs, fill the gallon jug to the top with water.


E.P.’s Healing Shampoo for Xolo skin.   (best for xolos with bumps & sores)

Betadine solution 4 oz. (50%)

Glycerin 2 oz. (25%)

Dish detergent (Planet or Ivory) 2 oz. (25%)


Ear Cleaning Solution for Xolos

Into a plastic squeeze bottle:  fill 3/4 with water & 1/4 with white vinegar.  Squirt this into the ear & massage the side of the head below the ear.  Use weekly before the bath.


Once a month put a few drops of olive oil into the Xolo’s ear and massage the head below the ear. This will soften any ear wax and prevent mites.

Hairless Xolos should be bathed and groomed once a week, including cleaning ears and clipping nails.  Coated Xolos can go longer between baths but need their ears cleaned and nails clipped every week.  For a hairless Xolo, follow the bath with a lotion, preferably one that contains cocoa butter. For any Xolo, a vinegar rinse promotes healthy skin. After the bath, fill a cup with warm water and add a splash of white vinegar. Pour this over the Xolo, saturating the skin. Do not rinse off.  Do not use a vinegar rinse if the dog has any open scratches or sores.


For the hairless dogs that develop large bumps, clogged glands, on their skin, it is helpful to use Sulfur Soap a few times a week. This can be ordered from www.naturalgenesis.com

Of course, hand in hand with grooming for a beautiful skin or coat we have to maintain excellent nutrition for our dog. Some skin problems are caused by sensitivity to the diet or enviroment. For information on this go to www.vetallergy.com

A short report on the recent article in Science magazine about the hairless gene in dogs.

The title of the article is “A Mutation in Hairless Dogs Implicates FOX13 in Ectodermal Development” The researchers are from Sweden, Finland, Swizerland and the Broad Institute of Harvard U. and  MIT The people from the University of Bern in Swizerland seem to be the prime researchers. They are Cord Drogemuller, Elinor Karlsson, Marjo K. Hytonen, Gaudenz Dolf, Kirsi Sainio, Hannes Lohi, Kersten Lindblad-Toh and Tosso Leeb.

The phenotype (physical appearance) of the hairless dog’s in the Xolo line is classified as Canine Ectodermal Dysplasia. This is the near complete absence of hair and the effect on the teeth.Teeth and hair are classified as ectodermal appendages, because they form very late in the development of the fetus.  There are also some alterations in some of the exocrine glands in the human form which are not severe in the living dogs. This might also explain why some hairless dogs sweat through their skin because in this condition in humans the sweat glands can also be affected.

Ectodermal dysplasia in humans is a disorder involving two or more of the ectodermal structures, which include the skin, hair, nails, teeth, mucous membranes and sweat glands. How an individual is affected varies. For example, in one individual the hair and nails may be affected, while in another the disorder may involve the sweat glands and teeth. Each combination is considered a distinct type of ectodermal dysplasia.

They traced the gene to the 17th chromosome on the dogs where a sequence that is part of what is known as a FOX gene is duplicated. The Fox family of genes (which have nothing to do with foxes) are an important group of about 50 genes that encode for developmental regulators. This duplication is only 7 base pairs long but acts as an early “stop” signal for the production of the regulators. With only 1 gene the amount of the regulator is decreased but appears to be completely missing in the dogs with the two dominant genes. The lack of this regulator is thought to be the reason why the homozygous pups die.

The study was done using 140 hairless dogs, Chinese Crested, Xoloitzcuintle and Peruvians. The duplication was found in all of the dogs. When they tested coated dogs of the three breeds (55) and 32 other dogs from 19 other coated breeds there was no duplication on the gene.

They commented that “This study illustrated how the extreme morphological (body type) diversity of dogs can be harnessed to gain new insights into developmental biology.”

Kacie Johnson 
Tucson Arizona